β-Nicotinamide Adenine Dinucleotide, abbreviated as NAD, is an essential core coenzyme widely present in all prokaryotic and eukaryotic living cells, playing a central role in biological oxidation and energy metabolism systems. Characterized by reversible redox properties, NAD can interconvert between NAD? and NADH forms. It acts as an electron transporter in critical metabolic pathways including glycolysis, tricarboxylic acid cycle and mitochondrial oxidative phosphorylation, driving ATP biosynthesis and sustaining basic cellular energy supply.

Beyond classic redox functions, NAD serves as a vital substrate for multiple key proteases such as PARPs, Sirtuins family sirtuins and CD38. It is deeply involved in DNA damage recognition and repair, cell cycle regulation, oxidative stress balance, inflammatory signal pathway modulation, cell apoptosis and aging-related biological processes. Numerous literature studies have verified that endogenous NAD levels gradually decline with aging. Therefore, this compound is widely adopted in in-vitro cell experiments and animal model research focusing on cellular senescence, metabolic disorders, neurodegenerative diseases and cardiovascular cell protection.

This research-grade NAD is produced via chemical synthesis with a comprehensive quality control protocol. Test items include HPLC purity, water content, heavy metal residues, endotoxin and related impurities. The lyophilization process effectively enhances product stability and slows degradation under ambient temperature. It features excellent water solubility and can be prepared into stock solutions with sterile deionized water or physiological buffer saline. The stability of liquid solution is far inferior to solid powder. Prepare freshly before use. Aliquot remaining stock solution and store in low temperature away from light to reduce activity loss caused by repeated freeze-thaw. No extra preservatives or bulking agents are added. Consistent quality across batches supports repeated control experiments, biochemical enzyme activity assays, cell culture intervention and various other research tests.