ARA?290, also known as Cibinetide or pHBSP (pyroglutamate helix B surface peptide), is a synthetic 11?amino?acid peptide derived from the helix?B surface domain of human erythropoietin (EPO)cenexalabs.... It selectively activates the innate repair receptor (IRR, EPOR/CD131 heterocomplex), without triggering erythropoiesis or red?blood?cell production, which differentiates it from full?length EPO protein. The N?terminal pyroglutamate modification improves peptide stability against aminopeptidase degradation for laboratory application.

In pre?clinical research, ARA?290 mediates anti?inflammatory, neuroprotective and tissue?repair related signaling pathways. It is widely used for studies covering nerve injury, neuropathic pain, tissue ischemia?reperfusion damage, wound?healing mechanism, inflammation response and organ protective biological experiments.

Our ARA?290 peptide is manufactured via solid?phase peptide synthesis under strict quality control. Each batch is verified by HPLC purity detection and MS molecular?weight identification. Complete COA, HPLC and MS documents can be supplied upon request. Lyophilized powder is sealed in inert?gas?filled glass vials to reduce moisture?caused degradation during transit and storage.