Retatrutide, coded LY3437943, is a 39-amino-acid synthetic peptide with triple receptor agonist activity. It is capable of simultaneously activating GLP-1, GIP and glucagon receptors, making it a critical research tool for exploring metabolic regulation and appetite modulation mechanisms. Widely applied in related pharmacological studies, this compound aids in in-depth research on human appetite regulation, glycemic homeostasis and energy metabolism mechanisms.