IGF-1 LR3, also known as Long R3 IGF-1, is a synthetic analog of Insulin-like Growth Factor 1 with amino acid modification. The structural alteration greatly reduces binding affinity to IGF binding proteins in biological systems, extending its half-life significantly compared with native IGF?1. This characteristic makes it a highly valuable research reagent for cell biology and endocrinology laboratory exploration.

Manufactured via solid-phase peptide synthesis and multi-stage reversed-phase HPLC purification, our IGF-1 LR3 undergoes comprehensive batch quality verification. Testing items cover HPLC purity detection, mass spectrometry confirmation, endotoxin level testing, moisture content measurement and residual organic solvent examination to maintain stable quality between batches. Lyophilization processing locks the molecular conformation, protecting biological activity during transit and long-term preservation.

In research scenarios, IGF-1 LR3 is widely utilized in cell culture, in vitro proliferation assays and animal model experiments. Researchers employ it to study cell proliferation, cell differentiation, tissue growth mechanisms and signal transduction pathways linked to insulin-like growth factor receptors. Once reconstituted, the solution should be divided into small-volume aliquots right away. Repeated freezing and thawing triggers peptide denaturation and activity attenuation. COA documents are available for every batch to satisfy experimental record keeping and repeatability requirements.