Epithalon (Epitalon, AEDG Tetrapeptide) CAS: 307297-39-8 Purity: ≥99% HPLC Appearance: White lyophilized powder Molecular Weight: 390.35 Da Sequence: Ala-Glu-Asp-Gly (AEDG) Storage: Store dry at -20°C, protect from light and moisture. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. Description: Epithalon, also known as Epitalon or AEDG tetrapeptide, is a synthetic research-grade peptide derived from pineal-related Epithalamin. It is widely studied in cellular aging, telomere maintenance, antioxidant defense, circadian rhythm and endocrine regulation research. 

Core Research Functions: 

1. Telomerase Activation Up-regulates hTERT expression and induces telomerase activity, supporting telomere elongation and maintaining genomic stability in somatic cells. 

2. Anti-Senescence and Antioxidant Effects Modulates aging-related gene expression, enhances endogenous antioxidant defense, and reduces oxidative cellular damage. 

3. Endocrine and Circadian Regulation Modulates pineal melatonin synthesis, helps normalize circadian rhythm and supports stress-related hormone balance. 

4. DNA Repair and Cellular Senescence May support DNA repair mechanisms, slow cellular senescence and maintain normal cell function under experimental conditions. Packaging: 10mg / 50mg / 100mg or custom packaging available.