SS?31, also known as Elamipretide or MTP?131, belongs to the Szeto?Schiller (SS) family, a synthetic aromatic?cationic tetrapeptide with unique mitochondria?targeting property. Thanks to its special alternating cationic?aromatic structure, SS?31 can easily cross cell membranes and highly accumulate within inner mitochondrial membrane, binding specifically to cardiolipin, the key phospholipid maintaining mitochondrial cristae structure and electron transport chain function.

In laboratory studies, SS?31 stabilizes cardiolipin structure, inhibits cardiolipin peroxidation, reduces reactive oxygen species (ROS) generation caused by electron leakage, improves mitochondrial bioenergetics and preserves ATP production, and alleviates oxidative?stress?induced mitochondrial damage. It is widely adopted in multiple research fields including mitochondrial function mechanism, ischemia?reperfusion injury, cardiac?muscle research, neurodegeneration study, aging?related mitochondrial decline and anti?oxidation biological experiments.

Our SS?31 peptide is chemically synthesized under strict quality management. Each batch undergoes HPLC purity detection and MS molecular weight verification. Complete COA, HPLC and MS reports can be provided upon request. The lyophilized powder is filled in inert?gas?sealed glass vials to reduce moisture and oxidation risk during transportation and storage.